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KMID : 0374919920130030353
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Inje Medical Journal
1992 Volume.13 No. 3 p.353 ~ p.362
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Histopathologic Changes and the Effect of Sodium Hyaluronate in the Alkali-Burned Rabbit Comea
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Abstract
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The influence of topically applied 2% Sodium hyaluronate (NaHA) and Phosphate buffer solution (PBS) was studied on the healing of rabbit corneal alkali wound, respectively.
NaHA have a positive influence on the epithelial re-surfacing, especially during the initial haling phase. In NaHA-group was observed mild stromal edema and smaller endothelial cell defect when compared with that in the PBS-group. No significant
difference in the repair process was observed between the NaHA-group and the PBS-group. However, NaHA is not the final solution to the treatment of corneal alkali wounds. It might exert a positive influence on the healing process and may serve as
an
adjunct in the clinical treatment of corneal alkali wounds.
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KEYWORD
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